CBD is a constituent of marijuana with pharmacological benefits without the addictive psychotropic effect of tetrahydrocannabinol (THC), another primary ingredient in cannabis. This currently commercially available non-neurotropic component has shown promise against arthritis pain by attenuating pro-inflammatory immune responses. If CBD can act remarkably, it can energize and stimulate a system of our organism; the endocannabinoid system.
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Arthritis is an inflammatory disease of the joints. When these are worn out, it reduces cartilage, flexible connective tissue that protects the joints. Stiffness, swelling, and pain occur and can limit the range of motion. Conventional treatment for this disease aims to strengthen the joints and reduce pain. However, it seems that this treatment is not efficient for everyone and that some still complain of debilitating chronic pain. We know oddly anecdotally from some people with arthritis that CBD reduced their symptoms.
Considering several patients’ opinions, it seems that using CBD for the inflammatory and painful symptoms of arthritis is possible. Even without large-scale human studies showing that it works for arthritis; people with the condition are entering the market. A survey conducted by Californian researchers among 2,500 participants, 62% of whom used CBD for a medical reason, revealed that chronic pain and joint pain are the two main conditions people take CBD for. The following three reasons are anxiety, depression, and insomnia. These are also symptoms often associated with arthritis.
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CBD is believed to act on pain in two parts of the body: the site of pain (like the joints) and the central nervous system, which sends pain signals to the brain when it senses stimulation or damage to the nerves and cells. Our nervous system contains a vanilloid receptor involved in transmitting pain signals. When these receptors are blocked or when their activity decreases, the sensation of pain also decreases. CBD acts on the vanilloid receptors, causing an analgesic effect, which helps to relieve the sensation of pain. buy Lyrica in thailand The best option for organic CBD oil for sale online http://chrisgraymusic.com/ .
How to take CBD for arthritis?
There are two methods that you can consume CBD; orally or topically. To take it orally, there is CBD oil or CBD gel capsules. For topical use, there are balms and lotions to be applied to the skin. But before we talk about the proper dosage of CBD, it’s essential to understand bioavailability first. By definition, bioavailability is: “the amount of a substance that becomes available (reaches the target organ or the circulation of the system) in the body of an organism for bioactivity when introduced by ingestion, inhalation, injection or skin contact ‘. As we have mentioned, CBD, taken orally, has shown low bioavailability due to an essential first pass known as the first-pass metabolism. It takes place in the intestine or the liver, and this is when much of the CBD is destroyed before it can circulate in the body. So, unless using the microencapsulation method to ensure delayed release of CBD to the site of action (avoid the first-pass metabolism), it would be best to opt for transdermal use.
What dosage to use?
Regarding dosage, there is no scientifically proven dosage of cannabidiol for any medical condition. This involves first establishing a base dosage and adjusting that dosage gradually over some time (usually three days) until one finds their effective dose. Therefore, it is appropriate for everyone in the company of their attending physician to find the proper dosage adapted to their situation.
Conclusion: However, although CBD may help relieve arthritis symptoms, it is not an alternative to conventional arthritis treatments, and it would be safer to consult your doctor before using it.